1 get ...out of the way first 先来说一说......

　　So, let's get the bad news out of the way first. 首先让我们来说一说坏消息。

　　2 regardless of 不顾，不管

　　She always travels first-class regardless of expense. 无论费用多高她总是乘头等舱。

　　Everyone has the right to good medical care regardless of their ability to pay. 无论支付能力如何，每个人都有权得到良好的医疗。

　　He went ahead and did it, regardless of the consequences. 他说干就干了，没有考虑后果。

　　The club welcomes all new members regardless of age. 俱乐部对所有新成员不分年龄一律欢迎。

　　3 in spite of 尽管；不管，不顾

　　They are firm friends in spite of temperamental differences. 他们尽管性格不同，但仍然友情甚笃。

　　In spite of many defeats, they still had plenty of fight left in them. 他们尽管多次失败，但仍然斗志昂扬。

　　In spite of his disappointment, he managed a weak smile. 尽管他很失望，他还是勉强露出一丝淡淡的微笑。

　　In spite of their quarrel, they remain the best of friends. 尽管有过争吵，他们仍是最好的朋友。

　　In spite of all her family problems, she's really in control. 她虽然家庭问题重重，却能完全处之泰然。

　　In spite of his illness, he clung tenaciously to his job. 尽管有病，他仍顽强地坚持工作。

　　4 as well as 也；和…一样；不但…而且

　　Coursework is taken into account as well as exam results. 

　　除考试结果外，课程作业也要计入成绩。

　　He plays classical music, as well as pop and jazz. 他演奏流行音乐和爵士乐，同时也演奏古典音乐。

　　It makes sense politically as well as economically. 这在经济上和政治上都有道理。

　　5 instead adv. 代替；反而；相反

　　She wasn't sent to the juvenile court; instead she was cautioned. 

　　她未被送上少年法庭，而是受到了警告。

　　He didn't reply. Instead, he turned on his heel and left the room. 

　　他没有回答，反而转身离开了房间。